RIL: Publications
Journal
Covers
Research
Papers
85. Didwischus, N., Guduru,
A., Badylak, S.F., Modo, M.
In vitro dose-dependent effects of matrix metalloproteinases (MMPs) on ECM
hydrogel biodegradation. Acta Biomateralia. 2023,
175:104-115. PMID: 38081445.
84. Modo, M., Sparling, K., Novotny, J. Perry, N., Foley, L.,
Hitchens, T.K. Mapping mesoscale connectivity in the human hippocampus.
Neuroimage. 2023, 282: 120406. PMID: 37827206.
83. Chung, J., Sun, D., Hitchens, T.K., Modo, M., Bandos, A., Mettenburg, J., Wang, P., Jin, T.
Dual contrast CEST MRI for pH-weighted imaging in stroke. Magnetic Resonance in
Medicine. 2024, 91(1): 357-367. PMID: 37798945.
82. McGraw, M., Gilmer, G., Bergmann, J., Seshan,
V., Wang, K., Pekker, D., Modo, M., Ambrosio, F. Mapping the landscape of
magnetic field effects on neural regeneration and repair: A systematic review,
mathematical model and meta-analysis. Journal of Tissue Engineering and
Regenerative Medicine. 2023: 5038317.
81. Fountain, C., Ghuman, H., Paldino, M., Tamber, M., A., Modo, M. Acquisition and analysis of excised
neocortex from pediatric patients with focal cortical dysplasia using mesoscale
diffusion MRI. Diagnostics. 2023, 13, 1529. PMID: 37174921.
80. Manivannan, A., Foley, L., Hitchens,
T.K., Rattray, I., Bates, G., Modo, M. Diffusion MRI-based tractography of
connectivity changes in the end-stage R6/2 mouse model of Huntington’s disease.
Neuroprotection. 2023. 1, 1-18. PMID: 7745674.
79. Patkar, S., Uwanogho, D., Modo, M.,
Tate, R., Plevin, R., Carswell, H.V.O. Targeting 17b-estradiol biosynthesis in
neural stem cells improves stroke outcome. Frontiers in Cellular Neuroscience.
2022, 16:917181. PMID: 35936502.
78. Modo, M., Ghuman, H., Azar, R., Krafty, R., Badylak, S.F.,
Hitchens, T.K. Mapping the acute time course of immune cell infiltration into
an ECM hydrogel in a rat model of stroke using 19F MRI.
Biomaterials. 2022, 282: 121386. PMID: 35093825.
77. Ghuman, H., Perry, N., Grice, L., Gerwig, M., Moorhead, J., Nitzsche,
F., Poplawsky, A., Ambrosio, F., Modo, M. Physical
therapy exerts sub-additive and suppressive effects on intracerebral neural
stem cell implantation in a rat model of stroke. Journal of Cerebral Blood Flow
and Metabolism. 2021, 41(1): 1-18. PMID: 34826373. Cover Image.
76. Damian, C., Ghuman, H., Mauney, C., Azar, R., Reinartz,
J., Badylak, S.F., Modo, M.
Post-stroke timing of ECM hydrogel implantation affects biodegradation and
tissue restoration. International Journal for Molecular Sciences. 2021, 22(21):
11372. PMID: 34768800.
75. Ghuman, H., Matta, R., Tompkins, A., Nitzsche, F., Badylak, S.,
Gonzalez, A., Modo, M. ECM hydrogel improves the delivery and retention of stem
cell encapsulating PEG microspheres in a stroke cavity. Brain Research
Bulletin. 2021, 168-120-137. PMID: 33373665.
74. Ke, J., Foley, L., Hitchens, T.K.,
Richardson, M., Modo, M. Ex vivo mesoscopic diffusion MRI correlates with
seizure frequency in patients with uncontrolled temporal lobe epilepsy. Human
Brain Mapping 2020; 41: 4529-4548. PMID: 326221364. Cover Image.
73. Ly, M., Foley, L., Manivannan, A.,
Hitchens, T.K., Richardson, M., Modo, M. Mesoscale diffusion MR imaging of the ex vivo human hippocampus. Human Brain
Mapping. 2020; 41(15):4200-4218. PMID: 32621364. Cover Image.
72. Chou, C.H. & Modo, M. Characterization of gene expression
changes in human neural stem cells and endothelial cells modeling a
neurovascular environment. Brain Research Bulletin. 2020; 158: 9-19. PMID: 32092433.
71. Ghuman, H., Hitchens, K., Modo, M. A
systematic optimization of 19F MR image acquisition to detect
macrophage invasion into an ECM hydrogel implanted in the stroke-damaged brain.
Neuroimage. 2019; 202. PMID: 31408717.
70. Ghuman, H., Mauney,
C., Donnelly, J., Massensini, A., Badylak,
S.F., Modo, M. Biodegradation of ECM hydrogel
promotes endogenous brain tissue restoration in a rat model of stroke. Acta Biomaterialia 2018; 80: 66-84. PMID: 30232030.
69. Wahlberg, B., Ghuman, H., Liu, J.R.,
Modo, M. Ex vivo biomechanical characterization of syringe-needle ejections for
intracerebral cell delivery. Scientific Reports. 2018; 8: 9194. PMID: 29907825.
68. Calvero, A., Cotel,
M.-C., Natesan, S., Modo, M., Vernon, A.C., Mondelli,
V. Effects of chronic antipsychotic treatment on expression of TSPO and
inflammatory markers in rat adipose tissue. Psychoneuroendocrinology.
2018; 95: 28-33. PMID: 29793094.
67. Liu, J, Modo, M. Quantification of the extracellular matrix
molecule thrombospondin 1 and its cellular association in the brain using a
semi-automated computerized approach. J Histochemistry & Cytochemistry.
2018; 66(9): 643-662. PMID: 29683384. Cover Image.
66. Jin, T., Iordanova,
B., Hitchens, T.K., Modo, M., Wang, P., Mehrens, H.,
Kim, S.G. Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and
analogs in brain tumors. Magnetic Resonance in Medicine. 2018; 80(2):488-495. PMID: 29569739.
65. Ghuman, H. Gerwig,
M., Nicholls, F.J., Liu, J., Donnelly, J., Badylak,
S.F., Modo, M. Long-term retention of ECM hydrogel
after implantation into a sub-acute stroke cavity reduces lesion volume. Acta Biomaterialia. 2017; 50-63. PMID: 28917705.
64. Dalise, S., Cavalli, L., Ghuman, H., Wahlberg, B., Gerwig,
M., Chisari, C., Ambrosio, F., Modo, M. Biological effects
of dosing aerobic exercise and neuromuscular electrical stimulation in rats.
Scientific Reports. 2017; 7(1): 10830. PMID: 28883534.
63. Modo, M., Crum, W.R., Gerwig, M.,
Vernon, A.C., Patel, P., Jackson, M.J., Rose, S., Jenner, P., Iravani, M.M. Magnetic resonance imaging and tensor-based
morphometry in the MPTP non-human primate model of Parkinson’s disease. PLOS1.
2017; 12(7): e0180733. PMID: 28738061.
62. Nicholls, F.J., Liu, J.R., Modo, M. A comparison of exogenous
labels for the histological identification of transplanted neural stem cells.
Cell Transplantation. 2017; 26: 625-645. PMID: 27938486. Cover Image.
61. Rattray, I., Smith, E., Crum, W., Walker, T., Bates, G., Modo,
M. Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the HdhQ150/Q150
mouse model of Huntington’s disease. PLOS1. 2017; 18(2): e0168556. PMID: 28088507.
60.
Jin, T., Nicholls, F.J., Ghuman, H., Badylak, S.F., Modo, M. Diamagnetic
chemical exchange saturation transfer (dia-CEST) affords magnetic resonance
imaging of extracellular matrix hydrogel implantation in a rat model of stroke.
Biomaterials. 2017; 113:176-190. PMID: 27816001.
59.
Crum, W.R., Danckaers, F., Huysmans, T., Natesan, S., Modo, M., Sijbers, J.,
Williams, S.C.R., Kapur, S., Vernon, A.C. Chronic treatment with haloperidol
and olanzapine leads to common and divergent shape changes in the rat
hippocampus in the absence of grey matter volume loss. Psychological Medicine.
2016; 46: 3081-3093. PMID: 27516217.
58.
Chou, C-H., Modo, M. Human neural stem cell-induced endothelial morphogenesis
requires paracrine and juxtacrine signaling. Scientific Reports. 2016; 6:
29029. PMID: 27374240.
57.
Ghuman, H., Massensini, A, Kim, T., Badylak, S.F., Modo, M. ECM hydrogel
injection for the treatment of stroke: Characterization of the acute host cell
invasion. Biomaterials. 2016; 91: 166-181. PMID: 27031811.
56.
Modo, M., Hitchens, T.K., Liu, J., Richardson, R.M. Ex vivo mesoscale diffusion
MRI reveals an aberrant collateral mossy fiber connection between dentate gyrus
and the stratum moleculare layer in a patient with uncontrolled temporal lobe
epilepsy. Human Brain Mapping. 2016; 37(2):780-795. PMID: 26611565.
55.
Rossetti, T., Nicholls, F., Modo, M. Intracerebral cell transplantation:
Preparation and characterization of cell suspensions. Cell Transplantation.
2016; 25: 645-664. PMID: 26720923.
54.
Nicholls, F., Rotz, M.W., Ling, W., Ghuman, H., MacRenaris, K.W., Meade, T.J.,
Modo, M. DNA-Gadolinium-Gold nanoparticles for in vivo T1 MR imaging of
transplanted human neural stem cells. Biomaterials. 2016; 77: 291-306. PMID: 26615367.
53.
Nicholls, F., Ling, W., Ferrauto, G., Aime, S., Modo, M. Simultaneous MR
imaging for tissue engineering in a rat model of stroke. Scientific Reports.
2015; 5: 14597. PMID: 26419200.
52.
Massensini, A., Ghuman, H., Medberry, C.J., Ling, W., Nicholls, F.J., Badylak,
S.F., Modo, M. Concentration-dependent intracerebral delivery of ECM hydrogel
to a stroke cavity. Acta Biomaterialia. 2015; 27:116-130. PMID: 26318805.
51.
Cotel, M.-C., Lenartowicz, E.M., Natesan, S., Modo, M., Cooper, J.D., Williams,
S.C.R., Kapur, S., Vernon, A.C. Region-specific microglia activation in the rat
brain following chronic antipsychotic treatment at clinically relevant doses.
European Neuropsychopharmacology. 2015; 25(11):2098-2107. PMID: 26321204.
50.
Caron, I., Micotti, E., Merlino, G., Plebani, L., Gianluigi, F., Modo, M.,
Bendotti, C. Comparative magnetic resonance imaging and histopathology
correlates in two SOD1 transgenic mouse models of amyotrophic lateral sclerosis.
PLOS1. 2015;10(7):e0132159. PMID: 26132656.
49.
Chou, C-H., Sinden, J.D., Couraud, P-O., Modo, M. In vitro modelling of the
neurovascular environment by coculturing adult human brain endothelial cells
with human neural stem cells. PLOS One. 2014: 9(9): e106346. PMID: 25187991.
48.
Rattray, I., Smith, E., Crum, W., Walker, T., Gale, R., Bates, G., Modo, M.
Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the R6/1 mouse model of HuntingtonÕs
disease. PLOS One. 2013: 8(12): e84726. PMID: 24367693.
47.
Chung, Y.-L., El Akabawy, G., So, P-W., Solanky, B., Leach, M.O., Modo, M.
Profiling metabolite change in the neuronal differentiation of human striatal
neural stem cells using 1H-magnetic resonance spectroscopy.
NeuroReport. 2013: 24(18);1035-1040. PMID: 24145773.
46.
Alfieri, A., Srivastava, S., Siow, R.C.M., Cash, D., Modo, M., Duchen, M.R.,
Fraser, P.A., Williams, S.C.R., Mann, G.E. Sulforaphane preconditioning of the
Nrf2/HO-1 defence pathway protects the cerebral vasculature against blood-brain
barrier disruption and neurological deficits in stroke. Free Radical Biology
and Medicine. 2013: 65C; 1012-1022. PMID: 24017972.
45.
Vernon, A.C., Crum, W.R., Lerch, J.P., Chege, W., Natesan, S., Modo, M.,
Cooper, J.D., Williams, S.C.R., Kapur, S. Reduced cortical volume and elevated
astrocyte density in rats chronically treated with antipsychotic drugs –
linking MRI findings to cellular pathology. Biological Psychiatry. 2014,
75(12):982-990. PMID: 24143881.
44.
Kazanis, I., Gorenkova, N., Zhao, J.-W., Franklin, RJM, Modo, M.,
ffrench-Constant, C. The late response of rat subependymal zone stem and
progenitor cells to stroke is restricted to directly affected areas of their
niche. Experimental Neurology. 2013: 248; 387-397. PMID: 23830949.
43.
Stille, M., Smith, E., Crum, W.R., Modo, M. 3D reconstruction of 2D
fluorescence histology images and registration with in vivo MR images:
Application in a rodent model of stroke. Journal of Neuroscience Methods. 2013:
219 (1); 27-40. PMID: 23816399.
42.
Crum, W.R., Giampietro, V.P., Smith, E.J., Gorenkova, N., Stroemer, R.P., Modo,
M. A comparison of automated anatomical-behavioural mapping methods in a rodent
model of stroke. Journal of Neuroscience Methods. 2013: 218 (2); 170-183. PMID: 23727124.
41.
Crum, W.R., Modo, M., Vernon, A.C., Barker, G.J., Williams, S.C.R. Registration
of challenging pre-clinical brain imaging. Journal of Neuroscience Methods,
2013: 216 (1); 62-77. PMID: 23558335.
40.
dellÕAcqua, F, Bodi, I., Slater, D., Catani, M., Modo, M. MR diffusion-based
histology and micro-tractography reveal mesoscale features of the human
cerebellum. Cerebellum, 2013:12(6); 923-931. PMID: 23907655.
39.
Rattray, I., Smith, E., Gale, R., Matsumoto, K., Bates, G.P., Modo, M.
Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the R6/2 mouse model of HuntingtonÕs
disease. PLoS One 2013: 8(4); e60012. PMID: 23593159.
38.
Mondelli, V, Anacker, C., Vernon, A.C., Cattaneo, A., Natesan, S., Modo, M.,
Dazzan, P., Kapur, S., Pariente, C. Haloperidol and olanzapine mediate
metabolic abnormalities through different molecular pathways. Translational
Psychiatry 2013: 3; e208. PMID: 23321805.
37.
Medberry, C.J., Crapo, P.M., Siu, B.F., Carruthers, C.A., Wolf, M.T., Nagarkar,
S., Agrawl, V., Jones, K.E., Kelly, J., Johnson, S.A., Sachin, V., Watkins,
S.C., Modo, M., Badylak. S.F. Hydrogels derived from central nervous system
extracellular matrix. Biomaterials. 2013: 34(4):1033-1040. PMID: 23158935.
36.
Puppi, J., Modo, M., Dhawan, A., Mitry, R.R., Hughes, R. Tracking transplanted
hepatocytes in a rat model of acute liver failure – is there a role for
cellular MRI? Cell Transplantation. 2014; 23(3):329-343. PMID: 23394812.
35.
El-Akabawy, G, Rattray, I., Johansson, S.M., Gale, R., Bates, G., Modo, M.
Implantation of undifferentiated and pre-differentiated human neural stem cells
in the R6/2 transgenic mouse model of HuntingtonÕs disease. BMC Neuroscience
2012: 13(1); 97. PMID: 22876937.
34.
Bible, E., Qutachi, O., Chau, D.Y., Alexander, M.R., Shakesheff, K.M., Modo, M.
Neo-vascularization of the stroke cavity by implantation of human neural stem
cells on VEGF-releasing PLGA microparticles. Biomaterials 2012: 33; 7435-7446. PMID: 22818980.
33.
Vernon, A.C., Natesan, S., Crum, W.R., Cooper, J.D., Modo, M., Williams,
S.C.R., Kapur, S. Contrasting effects of haloperidol and lithium on brain
structure: An MRI study with post-mortem confirmation. Biological Psychiatry.
2012: 71(10); 855-863. PMID: 22244831.
32.
Bible, E., DellÕAcqua, F., Solanky, B., Bladucci, A., Crapo, P., Badylak, S.F.,
Ahrens, E.T., Modo, M. Non-invasive imaging of transplanted human neural stem
cells and ECM scaffold remodelling in the stroke-damaged rat brain by 19F-
and diffusion-MRI. Biomaterials. 2012; 33, 2858-2871. PMID: 22244696.
31.
Smith, E.J., Stroemer, R.P., Gorenkova, N., Nakajima, M., Crum, W.R., Tang, E.,
Stevanato, L., Sinden, J.D., Modo, M. Implantation site and lesion topology
determine efficacy of a human neural stem cell line in a rat model of stroke.
Stem Cells, 30(4), 785-796. PMID: 22213183.
30.
Patkar, S., Tate, R., Modo, M., Pelvin, R. & Carswell, H.V.O. Conditionally
immortalised neural stem cells promote functional recovery and brain plasticity
after transient focal cerebral ischaemia in mice. Stem Cell Research. 2012:
8(1); 14-25. PMID:22099017.
29.
Vernon, AC, Smith, E., Stevanato, L., Modo, M. Selective activation of
metabotropic glutamate receptor 7 reduces proliferation and promotes astrocyte
differentiation in human ventral mesencephalic neural stem cells.
Neurochemistry International. 2011, Sep;59(3)421-31. Epub 2011 May 23 PubMed PMID: 21624409.
28.
Vernon AC, Crum WR, Johansson SM, Modo M. Evolution of extra-nigral damage
predicts behavioural deficits in a rat proteasome inhibitor model of
Parkinson's disease. PLoS One. 2011 Feb 25;6(2):e17269. PubMed PMID: 21364887.
27.
El Akabawy G, Martinez-Medina L, Jeffries AR, Price J, Modo M. Purmorphamine
increases DARPP-32 differentiation in human striatal neural stem cells through
the hedgehog pathway. Stem Cells Dev. 2011 Feb 23. [Epub ahead of print] PubMed
PMID: 21345011.
26.
Vernon AC, Natesan S, Modo M, Kapur S. Effect of Chronic Antipsychotic
Treatment on Brain Structure: A Serial Magnetic Resonance Imaging Study with Ex
Vivo and Postmortem Confirmation. Biol Psychiatry. 2011 May 15;69(10):936-44.
[Epub 2010 Dec 31] PubMed PMID: 21195390.
25.
Puppi J, Mitry RR, Modo M, Dhawan A, Raja K, Hughes RD. Use of a
Clinically-Approved Iron Oxide MRI Contrast Agent to Label Human Hepatocytes.
Cell Transplant. 2010 Nov 19. [Epub ahead of print] PubMed PMID: 21092412.
24.
Vernon AC, Johansson SM, Modo MM. Non-invasive evaluation of nigrostriatal
neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
BMC Neurosci. 2010 Jan 5;11:1. PubMed PMID: 20051106; PubMed Central PMCID: PMC2824797.
23.
Bible E, Chau DY, Alexander MR, Price J, Shakesheff KM, Modo M. Attachment of
stem cells to scaffold particles for intra-cerebral transplantation. Nat
Protoc. 2009;4(10):1440-53. Epub
2009 Sep 17. PubMed PMID: 19798079.
22.
Ashioti M, Beech JS, Lowe AS, Bernanos M, McCreary A, Modo MM, Williams SC.
Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy
for a novel 5HT(1A) agonist in rat models of ischaemic stroke. BMC Neurosci.
2009 Jul 16;10:82. PubMed PMID: 19607699; PubMed Central PMCID: PMC2720976.
21.
Bible E, Chau DY, Alexander MR, Price J, Shakesheff KM, Modo M. The support of
neural stem cells transplanted into stroke-induced brain cavities by PLGA
particles. Biomaterials. 2009 Jun;30(16):2985-94. Epub 2009 Mar 10. PubMed PMID: 19278723.
20.
Badin RA, Modo M, Cheetham M, Thomas DL, Gadian DG, Latchman DS, Lythgoe MF.
Protective effect of post-ischaemic viral delivery of heat shock proteins in
vivo. J Cereb Blood Flow Metab. 2009 Feb;29(2):254-63. Epub 2008 Sep 10. PubMed
PMID: 18781161; PubMed Central PMCID: PMC2702130.
19.
Roberts TJ, Williams SC, Modo M. A pharmacological MRI assessment of
dizocilpine (MK-801) in the 3-nitroproprionic acid-lesioned rat. Neurosci Lett.
2008 Oct 17;444(1):42-7. Epub 2008 Aug 5. PubMed PMID: 18703114.
18.
Johansson S, Price J, Modo M. Effect of inflammatory cytokines on major
histocompatibility complex expression and differentiation of human neural
stem/progenitor cells. Stem Cells. 2008 Sep;26(9):2444-54. Epub 2008 Jul 17.
PubMed PMID: 18635871.
17.
Modo M, Beech JS, Meade TJ, Williams SC, Price J. A chronic 1 year assessment
of MRI contrast agent-labelled neural stem cell transplants in stroke.
Neuroimage. 2009 Aug;47 Suppl 2:T133-42. Epub 2008 Jun 25. PubMed PMID: 18634886.
16.
Brekke C, Williams SC, Price J, Thorsen F, Modo M. Cellular multiparametric MRI
of neural stem cell therapy in a rat glioma model. Neuroimage. 2007 Sep
1;37(3):769-82. Epub 2007 Jun 14. PubMed PMID: 17613248.
15.
Bae JS, Han HS, Youn DH, Carter JE, Modo M, Schuchman EH, Jin HK. Bone
marrow-derived mesenchymal stem cells promote neuronal networks with functional
synaptic transmission after transplantation into mice with neurodegeneration.
Stem Cells. 2007 May;25(5):1307-16. PubMed PMID: 17470534.
14.
Ashioti M, Beech JS, Lowe AS, Hesselink MB, Modo M, Williams SC. Multi-modal
characterisation of the neocortical clip model of focal cerebral ischaemia by MRI,
behaviour and immunohistochemistry. Brain Res. 2007 May 11;1145:177-89. Epub
2007 Feb 2. PubMed PMID: 17320839.
13.
Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC,
Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA. IGF-binding
protein-2 protects against the development of obesity and insulin resistance.
Diabetes. 2007 Feb;56(2):285-94. PubMed PMID: 17259371.
12.
Roberts TJ, Price J, Williams SC, Modo M. Pharmacological MRI of stem cell
transplants in the 3-nitropropionic acid-damaged striatum. Neuroscience. 2007
Jan 5;144(1):100-9. Epub 2006 Oct 19. PubMed PMID: 17055178.
11.
Brekke C, Morgan SC, Lowe AS, Meade TJ, Price J, Williams SC, Modo M. The in
vitro effects of a bimodal contrast agent on cellular functions and
relaxometry. NMR Biomed. 2007 Apr;20(2):77-89. PubMed PMID: 16952123.
10.
Roberts TJ, Price J, Williams SC, Modo M. Preservation of striatal tissue and
behavioral function after neural stem cell transplantation in a rat model of
Huntington's disease. Neuroscience. 2006;139(4):1187-99. Epub 2006 Mar 6.
PubMed PMID: 16517087.
9.
Modo M, Mellodew K, Cash D, Fraser SE, Meade TJ, Price J, Williams SC. Mapping
transplanted stem cell migration after a stroke: a serial, in vivo magnetic
resonance imaging study. Neuroimage. 2004 Jan;21(1):311-7. PubMed PMID: 14741669.
8.
Modo M, Hopkins K, Virley D, Hodges H. Transplantation of neural stem cells
modulates apolipoprotein E expression in a rat model of stroke. Exp Neurol.
2003 Oct;183(2):320-9. PubMed PMID: 14552873.
7.
Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of
dead stem cells in rats with stroke damage. Neuroreport. 2003 Jan
20;14(1):39-42. PubMed PMID: 12544827.
6.
Modo M, Mellodew K, Rezaie P. In vitro expression of major histocompatibility class
I and class II antigens by conditionally immortalized murine neural stem cells.
Neurosci Lett. 2003 Feb 6;337(2):85-8. PubMed PMID: 12527394.
5.
Modo M, Rezaie P, Heuschling P, Patel S, Male DK, Hodges H. Transplantation of
neural stem cells in a rat model of stroke: assessment of short-term graft
survival and acute host immunological response. Brain Res. 2002 Dec
20;958(1):70-82. PubMed PMID: 12468031.
4.
Modo M, Cash D, Mellodew K, Williams SC, Fraser SE, Meade TJ, Price J, Hodges
H. Tracking transplanted stem cell migration using bifunctional, contrast
agent-enhanced, magnetic resonance imaging. Neuroimage. 2002 Oct;17(2):803-11.
PubMed PMID: 12377155.
3.
Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of
stem cell grafts on behavioral recovery from stroke damage. Stroke. 2002
Sep;33(9):2270-8. PubMed PMID: 12215598.
2.
Modo M, Stroemer RP, Tang E, Veizovic T, Sowinski P, Hodges H. Neurological
sequelae and long-term behavioural assessment of rats with transient middle
cerebral artery occlusion. J Neurosci Methods. 2000 Dec 15;104(1):99-109.
PubMed PMID: 11163416.
1. Modo
M, Sowinski P, Hodges H. Conditional discrimination learning in rats with
global ischaemic brain damage. Behav Brain Res. 2000 Jun 15;111(1-2):213-21.
PubMed PMID: 10840146.
Reviews
31. Liu, J., van Beusekom, H., Bu, Z.-L.,
Chen, X., Clarkson, A.N., Farr, T.D., Fu, Y., Rosado de Castro, P.H., Jolkkonen, J., Kim, W.S., Korhonen, P. Li, S., Liang, Y.,
Liu, G., Liu, Y.-H., Malm, T., Mao, X., Oliveira,
J.M., Modo, M., Ramos-Ber, P., Ruscher, K., Song, W.,
Wang, J., Wang, X., Wang, Y., Wu, H., Xiong, L.,
Yang, L., Yang, Y., Ye, K., Yu, J.-T., Zhou, X.-F., Zille, M., Walczak, P., Boltze, J., Ji, X., Wang, Y.-J. Preserving cognitive
function in Alzheimer’s disease” The Alzheimer’s disease neuroprotection
research initiative (ADNRI). Neuroprotection. In press.
30. Hussein, H., Kokkinos, V., Sisterson,
N.D., Modo, M., Richardson, R.M. Extrapial
hippocampal resection in anterior temporal lobectomy: Technical description and
clinical outcomes. Operative Neurosurgery. 2021. 21(5): 312-323. PMID: 34333663.
29. Modo, M. 19F magnetic resonance imaging in
neuroscience. Neuroscience. 2021:474:37-50. PMID: 33766776.
28. Modo, M. Bioscaffold-induced brain tissue restoration.
Frontiers in Neuroscience. 2019; 13:1156. PMID: 31787865.
27. Boltze, J., Modo, M., Mays, R.R.,
Taguchi, A., Zille, M., Jolkkonen, J., Savitz, S. Stem cells as an emerging paradigm in stroke
(STEPS) 4: Advancing and accelerating preclinical research. Stroke. 2019;
50(11):3299-3306. PMID: 31658004.
27. Modo, M. & Badylak, S.F. A roadmap
for promoting endogenous in situ tissue restoration using inductive
bioscaffolds after acute brain injury. Brain Research Bulletin. 2019; 150:
136-149. PMID: 31128250.
26. Modo, M., Jolkkonen, Zille, M., Boltze, J. Future of animal modeling for poststroke tissue repair. Stroke. 2018;
49(5): 1099-1106. PMID: 29669872.
25. Amer, M.H., Rose, F.R.A., Shakesheff,
K.M., Modo, M., White, L.J. Translational
considerations for injectable cell-based therapeutics: Concepts, progress and
challenges. Npj Regenerative Medicine. 2017; 2(1):
23. PMID: 29302358.
24. Ghuman, H., & Modo, M.
Biomaterial applications in neural therapy and repair. Chinese Neurosurgical
Journal. 2016;2: 34.
23. Modo, M. Gaining mechanistic insights into cell therapy using
magnetic resonance imaging. Current Stem Cell Reports. 2016; 2(3); 221-227.
22. Dalise, S., Ambrosio, F., Modo, M.
Brain plasticity and recovery in preclinical models of stroke. Archives Italiennes de Biologie. 2014;
152(4): 190-215. PMID: 25987181. Cover Image.
21. Naumova, A.V., Modo, M., Moore, A., Murry, C.E., Frank,
J.A. Clinical imaging in regenerative medicine. Nature Biotechnology. 2014;
32(8): 804-818. PMID: 25093889.
20. Meng, F.W., Modo, M., & Badylak,
S.F. Biologic scaffold for central nervous system repair. Regenerative
Medicine. 2014; 9(3): 367-383. PMID: 24935046.
19. Savitz, S., Cramer, S.,
Wechsler, L., Aronowski, J., Boltze,
J., Borlongan, C., Chase, T., Chopp,
M., Carmichael, S.T., Fischkoff, S., Guzman, R.,
Hess, D., Huang, D., Hinson, J., Mitsias, P., Modo,
M., Muir, K., Steinberg, G., Wolf, S., Yankee, E. Stem cells as an emerging
paradigm for stroke (STEPS3): enhancing the development of clinical trials.
Stroke. 2014: 45(2); 634-639. PMID: 24368562.
18. Modo, M., Ambrosio, F., Friedlander, R., Badylak, S.F., Wechsler, L. Bioengineering solutions for neural
repair and recovery in stroke. Current Opinion in Neurology. 2013: 26(6);
626-631. PMID: 24136127.
17. Modo, M., Kolosnjaj, J.,
Nicholls, F., Ling, W., Wilhelm, C., Debarge, O., Gazeau, F., Clement, O. Considerations for the clinical use
of MRI contrast agents for cell tracking in regenerative medicine. Contrast
Media and Molecular Imaging. 2013: 8(6); 439-455. PMID: 24375900.
16. Sztriha, L., Modo, M.,
Gorman, R., Baker, G., Williams, S.C., Kalra, L. Monitoring brain repair in
stroke using advanced magnetic resonance imaging. Stroke, 2012;
43(11):3124-3131. PMID:23010674..
15. Evans, M.C., Modo, M., Talbot, K., Sibson, N., Turner,
M.R. Magnetic resonance imaging of pathological processes in rodent models of
amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis. 2012; 13(3);
288-301. PMID: 22117132.
14. Modo, M.
& Kinchin, I. (2011). A conceptual framework for
interdisciplinary curriculum design: A case study in neuroscience. Journal of
Undergraduate Neuroscience Education, 10(1), A71-A79. PMID: 23626496.
13. Alfieri A, Srivastava S, Siow
R, Modo M, Fraser P, Mann GE. Targeting the
Nrf2-Keap1 antioxidant defence pathway for
neurovascular protection in stroke. J Physiol. 589: 4125-4136. PubMed PMID: 21656410.
12. Kateb B, Chiu K, Black KL,
Yamamoto V, Khalsa B, Ljubimova
JY, Ding H, Patil R, Portilla-Arias
JA, Modo M, Moore DF, Farahani K, Okun MS, Prakash N,
Neman J, Ahdoot D, Grundfest
W, Nikzad S, Heiss JD.
Nanoplatforms for constructing new approaches to cancer treatment, imaging, and
drug delivery: what should be the policy? Neuroimage. 2011 Jan; 54 Suppl 1:S106-24. PubMed PMID: 20149882.
11. Turner, M., Modo, M. Recent advances in the MR imaging
of Amyotrophic Lateral Sclerosis. Expert Opinion on Medical Diagnostics. 2010
4(6), 483-496. PubMed PMID: 215116259.
10. Vernon AC, Ballard C, Modo M. Neuroimaging for Lewy
body disease: is the in vivo molecular imaging of a-synuclein neuropathology
required and feasible? Brain Res Rev. 2010 Oct 5;65(1):28-55. Epub 2010 Jun 2. Review. PubMed PMID: 20685363.
9. Modo M. Long-term survival and serial assessment of
stroke damage and recovery – practical and methodological considerations.
Journal of Experimental Stroke and Translational Medicine. 2010 2, 52-68.
8. Puppi J, Modo
M. Use of magnetic resonance imaging contrast agents to detect transplanted
liver cells. Top Magn Reson
Imaging. 2009 Apr;20(2):113-20. Review. PubMed PMID: 20010066.
7. Modo M. Noninvasive imaging of transplanted cells. Curr Opin Organ Transplant. 2008
Dec;13(6):654-8. Review. PubMed PMID: 19060558.
6. Modo M. Brain repair how stem cells are changing
neurology. Bull Soc Sci Med Grand Duche Luxemb. 2008;(2):217-57. Review. PubMed PMID: 18561598.
5. Modo M. Understanding stem cell-mediated brain repair
through neuroimaging. Curr Stem Cell Res Ther. 2006 Jan;1(1):55-63. Review. PubMed PMID: 18220854.
4. Schaller BJ, Modo M, Buchfelder M. Molecular imaging of brain tumors: a bridge
between clinical and molecular medicine? Mol Imaging Biol. 2007
Mar-Apr;9(2):60-71. Review. PubMed PMID: 17203238.
3. Modo M, Hoehn M, Bulte JW.
Cellular MR imaging. Mol Imaging. 2005 Jul-Sep;4(3):143-64. Review. PubMed PMID: 16194447.
2. Modo M, Roberts TJ, Sandhu JK, Williams SC. In vivo
monitoring of cellular transplants by magnetic resonance imaging and positron
emission tomography. Expert Opin Biol
Ther. 2004 Feb;4(2):145-55. Review. PubMed PMID: 14998774.
1. Modo M, Williams SCR. Molecular imaging by magnetic
resonance imaging: The next generation. Rivista di Neuroradiologia. 2003 16(Suppl 2), 23-27.
Book Chapters
21. Didwischus, N., Kisel, A., Modo, M. (in press). Endogenous in situ tissue
regeneration using inductive bioscaffolds after acute brain injury. In, Peplow, P., Martinez, B., Gennarelli,
T.A. (Eds). Regenerative
Medicine and Brain Repair. Springer Nature.
20. Modo, M. Didwischus, N., Kisel, A. (in press). An overview of non-invasive imaging
strategies in neural engineering. In Willerth, S.
(Ed.). Handbook of Neural Engineering. Elsevier.
19. Modo, M., Hitchens, T.K. (in press). 19F MRI
to map the spatio-temporal infiltration of immune
cells in stroke and tissue engineering. In Ahrens, E.T., Flögl,
U. (Eds). Fluorine magnetic resonance imaging: Methods and applications in
biomedicine. Jenny Stanford Publishing.
18. Dukes, M.W., Modo, M., Meade, T.J. (2022). Non-invasive
detection of stem cell therapies facilitated by metal ion-based contrast
agents. In Meade, T.J. (Ed.). Molecular
bio-sensors and the role of metal ions. CRC press.
17. Bulte, J.W. & Modo, M. (2016). Nanoparticles as a technology platform for
biomedical imaging. In Bulte, J.W. & Modo, M. (Eds.). Design
and applications of nanoparticles in biomedical imaging.
Springer Verlag.
16. Modo, M., Braga, R. & Ray, H. (2015). In vivo
imaging of transplanted cells and biomaterials. In Vishawakarma,
A., Shi, S., Sharpe, P., Wang, X. Ramalingam, M (Eds), Stem
Cell Biology and Tissue Engineering in Dental Sciences.
Elsevier.
15. Modo, M. & Massensini, A.
(2014). Repairing the stroke-damaged brain: From neural stem cells to tissue
engineering. In Hayat, M.A. (Ed.), Stem
Cells and Cancer Stem Cells (Vol 12). Springer Verlag.
14. Chung, C.H., Nicholls, F., & Modo, M. (2013).
Image-guided injection and non-invasive monitoring of regeneration in the
stroke-damaged brain. In Walczak, P. & Jolkkonen,
J. (Eds), Cell-based
therapies in stroke. CRC Press.
13. Nicholls, F., Gorenkova,
N., Bible, E., Franco, C., Chau, D.Y., Shakesheff,
K.M., West, J.L., Modo, M. (2013). Improving the treatment of stroke through
nanotechnology. In Heiss, J.D. & Kateb, B (eds), Nanoneurosurgery
and nanoneuroscience.
CRC Press.
12. Modo, M. (2011). Tracking
transplanted cells by MRI – methods and protocols. In Faber, C. &
Schroeder, L. (Eds.). In vivo NMR imaging: Methods and protocols. Humana Press.
PMID:
21874504.
11. Vernon, A., & Modo, M. (2011).
Imaging proteasome inhibition damage using MRI. In Modo, M. & Bulte, J.W. (Eds.). Neuroimaging – protocols and methods.
Series: Methods in Molecular Biology, 711, 487-510. Humana Press. PMID:21279619.
10. Modo, M. & Bulte,
J.W. (2011). Imaging from molecules to man – the dawn of a vitrious
man. In Modo, M. & Bulte, J.W.
(Eds.). Neuroimaging – protocols and
methods. Series: Methods in
Molecular Biology, 711, 3-14. Humana Press. PMID:21279595.
9. Modo, M., Meade, T.J. & Mitry, R. (2009). Liver cell labelling with MRI contrast
agents (Chapter 17). In Dhawan, A., Hughes, R. (Eds.), Hepatocyte
Transplantation. Series: Methods in Molecular Biology, 481, 207-219. Humana
Press. PMID:19096799.
8. Bulte,
J.W.M. & Modo, M. (2008). The emergence of
nanoparticles as a platform technology in biomedical imaging. In Bulte, J.W.M. & Modo, M.
(Eds), Nanoparticles
in biomedical imaging: Emerging technologies and applications.
Springer Verlag.
7. Modo, M., Price, J., & Williams,
S.C.R. (2008). Cell transplantation after stroke: The role of in vivo imaging.
In Schaller, B. (Ed), State-of-the-art
imaging in stroke: The present state and implication on future.
Nova Medical Publishers.
6. Modo, M. & Bulte,
J.W.M. (2007). What is molecular and cellular imaging? In Modo, M. & Bulte, J.W.M. (Eds), Molecular
and Cellular MR Imaging. CRC press.
5. Modo, M. & Bulte,
J.W.M. (2007). Cellular imaging of cell transplants. In Modo, M. & Bulte, J.W.M. (Eds), Molecular
and Cellular MR Imaging. CRC press.
4. Modo, M. & Bulte,
J.W.M. (2007). The outlook of molecular and cellular MR imaging. In Modo, M.
& Bulte, J.W.M. (Eds), Molecular
and Cellular MR Imaging. CRC press.
3. Modo, M. (2007). Are stem cells
attracted by pathology? – The case for serial in vivo magnetic resonance
imaging. In Fromes, Y., Tavitian,
B., Ntziachristos, V., Leroy-Willig, A. (Eds), In
vivo imaging in vertebrates. John Wiley & Sons.
2. Modo, M.,
& Williams, S.C.R. (2003). MRI and novel contrast agents for molecular
imaging (pp 293-322). In van Bruggen, N. &
Roberts, T. (Eds). Techniques of Biomedical Imaging in Neuroscience
Research. Boca Raton, FL: CRC Press.
1. Modo, M., Zelaya, F., Lythgoe, D., Beech, J.S., & Williams, S.C.R. (2002). Contemporary neuroimaging of cerebral ischaemia (pp 37-56). In Krieglstein, J. (Ed), Pharmacology of Cerebral Ischemia 2002. Stuttgart, Germany: Medpharm Scientific Publishers.
Books
3. Modo, M. & Bulte, J.W. (2011). MR Neuroimaging
– protocols and methods. Humana Press.
2. Bulte,
J.W.M. & Modo, M. (2008). Nanoparticles
in Imaging. Springer Verlag.
1. Modo, M.
& Bulte, J.W.M. (2007). Molecular and Cellular MR imaging. CRC Press.
