Profile Detail
Sina Tavakoli, MD, PhD
Associate Professor and Chief of Cardiothoracic ImagingE-Mail:
Interest (in 3 to 10 words): Cardiothoracic Radiology
| Education | |
| Medical / Graduate School | MD: Tehran University of Medical Sciences PhD: University of Texas Health Science Center at San Antonio |
| Residency | University of Texas Health Science Center at San Antonio |
| Clinical / Post-doctoral Fellowship | Clinical Fellowship: University of Washington Postdoctoral Fellowship: Yale University & University of Southern California |
| Current | |
| Specialties & Programs |
PET MR CT Nuclear Medicine Clinical Pre-clinical Translational |
| Clinical Interest | - Cardiac and Thoracic Radiology |
| Research Interest | - Molecular imaging of inflammation and extracellular matrix remodeling in pulmonary and cardiovascular diseases - Macrophage immunometabolism |
| Selected Publications | - Mannes PZ, Adams TS, Farsijani S, Barnes CE, Latoche JD, Day KE, Nedrow JR, Ahangari F, Kaminski N, Lee JS, Tavakoli S. Noninvasive assessment of the lung inflammation-fibrosis axis by targeted imaging of CMKLR1. Science Advances. 2024; 10(25):eadm9817. - Haddad J, Demirdelen S, Barnes CE, Leers SA, Tavakoli S. In situ mapping of the glucose metabolism heterogeneity in atherosclerosis: Correlation with 2-deoxyglucose uptake. Molecular Imaging. 2024; 23:15353508241280573. - Mannes PZ, Barnes CE, Biermann J, Latoche JD, Day KE, Zhu Q, Tabary M, Xiong Z, Nedrow JR, Izar B, Anderson CJ, Villanueva FS, Lee JS, Tavakoli S. Molecular Imaging of Chemokine-Like Receptor 1 (CMKLR1) in Experimental Acute Lung Injury. Proceedings of the National Academy of Sciences (PNAS). 2023; 120(3): e2216458120. - Zhu Q, Barnes CE, Mannes PZ, Latoche JD, Day KE, Nedrow JR, Novelli EM, Anderson CJ, Tavakoli S. Noninvasive imaging of very late antigen-4 in fibrotic lung injury. European Journal of Nuclear Medicine and Molecular Imaging Research. 2023; 13(1):55. - Mannes PZ, Barnes CE, Latoche JD, Day KE, Nedrow JR, Lee JS, Tavakoli S. 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to monitor lung inflammation and therapeutic response to dexamethasone in a murine model of acute lung injury. Molecular Imaging and Biology. 2023; 20:1-11. - Demirdelen S, Mannes PZ, Aral AM, Haddad J, Leers SA, Gomez D, Tavakoli S. Divergence of acetate uptake in polarized macrophages: Implications for imaging atherosclerosis. Journal of Nuclear Cardiology. 2022; 29(3):1266-1276. - Mannes PZ, Tavakoli S. Imaging immunometabolism in atherosclerosis. Journal of Nuclear Medicine. 2021; 62(7):896-902. - Haddad J, Latoche JD, Nigam S, Bellavia MC, Day KE, Zhu Q, Edwards WB, Anderson CJ, Tavakoli S. Molecular Imaging of Very Late Antigen-4 in Acute Lung Injury. Journal of Nuclear Medicine. 2021;62(2):280-286. - Tavakoli S, Short JD, Downs K, Nguyen HN, Lai Y, Zhang W, Jerabek P, Goins B, Sadeghi MM, Asmis R. Differential Regulation of Macrophage Glucose Metabolism by M-CSF and GM-CSF: Implications for 18F-FDG PET Imaging of Vessel Wall Inflammation. Radiology. 2017; 283(1):87-97. - Tavakoli S, Downs K, Short JD, Nguyen HN, Lai Y, Jerabek P, Goins B, Toczek J, Sadeghi MM, Asmis R. Improved Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation: Implications for Imaging of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 2017;37(10):1840-1848. - Tavakoli S, Vashist A, Sadeghi MM. Molecular Imaging of Plaque Vulnerability. Journal of Nuclear Cardiology. 2014; 21(64), 1112-28. - Tavakoli S, Zamora D, Ullevig S, Asmis R. Bioenergetic Profiles Diverge During Macrophage Polarization: Implications for the Interpretation of 18F-FDG PET Imaging of Atherosclerosis. Journal of Nuclear Medicine. 2013; 54(9): 1661-7. - Tavakoli S, Asmis R. Reactive Oxygen Species and Thiol Redox Signaling in the Macrophage Biology of Atherosclerosis. Antioxidants & Redox Signaling. 2012;17(12):1785-1795. - Restrepo CS, Tavakoli S, Marmol-Velez A. Contrast Enhanced Cardiac Magnetic Resonance Imaging. MRI Clinics of North America. 2012; 20(4):739-60. - Tavakoli S, Razavian M, Zhang J, Nie L, Marfatia R, Dobrucki LW, Sinusas AJ, Robinson S, Edwards DS, Sadeghi MM. Matrix metalloproteinase activation predicts amelioration of remodeling following dietary modification in injured arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011; 31(1):102-9. - Tavakoli S, Sadeghi MM. Imaging of Vascular Biology in the Heart. Current Cardiovascular Imaging Reports. 2009;2(1):40-9. |
| Honors and Awards |
2024 - University of Pittsburgh Senior Vice Chancellors Research Award 2022: Editors Recognition Award for Reviewing with Special Distinction, Radiology: Cardiothoracic Imaging 2020: Editors Recognition Award for Reviewing with Distinction, Radiology: Cardiothoracic Imaging 2016: RSNA Roentgen Resident/Fellow Research Award 2015: Editors Recognition Award for Reviewing with Distinction, Radiology 2013: RSNA William W. Olmsted Editorial Fellowship 2009: RSNA Young Investigator Award in Molecular Imaging |
| PubMed Publications | See a listing of publications on PubMed, a service of the National Library of medicine. |
